Crosstalk between the muscular estrogen receptor α and BDNF/TrkB signaling alleviates metabolic syndrome via 7,8-dihydroxyflavone in female mice

Objective: 7,8-Dihydroxyflavone (7,8-DHF), a small molecular mimetic of brain-derived neurotrophic factor (BDNF), alleviates high-fat diet-induced obesity in female mice in a sex-specific manner by activating muscular tropomyosin-related kinase B (TrkB). However, the underlying molecular mechanism f...

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Main Authors: Zhenlei Zhao (Author), Fan Xue (Author), Yanpei Gu (Author), Jianxin Han (Author), Yingxian Jia (Author), Keqiang Ye (Author), Ying Zhang (Author)
Formato: Livro
Publicado em: Elsevier, 2021-03-01T00:00:00Z.
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