Simvastatin-Encapsulated Topical Liposomal Gel for Augmented Wound Healing: Optimization Using the Box-Behnken Model, Evaluations, and In Vivo Studies

• Main Authors: Mohamed Rahamathulla (Author), Rahul Pokale (Author), Yousef Al-ebini (Author), Riyaz Ali M. Osmani (Author), Kamal Y. Thajudeen (Author), Ravi Gundawar (Author), Mohammed Muqtader Ahmed (Author), Syeda Ayesha Farhana (Author), Thippeswamy Boreddy Shivanandappa (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Statins function beyond regulating cholesterol and, when administered systemically, can promote wound healing. However, studies have yet to explore the topical use of statins for wound healing. The present study demonstrated the topical administration of SIM and aimed to formulate, evaluate, and opt...