A Buried Water Network Modulates the Activity of the <i>Escherichia coli</i> Disulphide Catalyst DsbA

• Päätekijät: Geqing Wang (Tekijä), Jilong Qin (Tekijä), Anthony D. Verderosa (Tekijä), Lilian Hor (Tekijä), Carlos Santos-Martin (Tekijä), Jason J. Paxman (Tekijä), Jennifer L. Martin (Tekijä), Makrina Totsika (Tekijä), Begoña Heras (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The formation of disulphide bonds is an essential step in the folding of many proteins that enter the secretory pathway; therefore, it is not surprising that eukaryotic and prokaryotic organisms have dedicated enzymatic systems to catalyse this process. In bacteria, one such enzyme is disulphide bon...