Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity

• Autores principales: Radwa El- Sayed Mahmoud Marie (Autor), Noha M. Abd El-Fadeel (Autor), Yara El-Sayed Marei (Autor), Lina M. Atef (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2022-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background. Alopecia areata (AA) is an acquired hair loss disorder induced by a cell-mediated autoimmune attack against anagen hair follicles. CD27-CD70 is a receptor-ligand complex which enhances T helper and cytotoxic T cell activation, survival, and proliferation. The overstimulation of this comp...