Pharmacogenetics of taxane‐induced neurotoxicity in breast cancer: Systematic review and meta‐analysis

• Main Authors: Alberto Guijosa (Author), Ana Freyria (Author), Jose Rodrigo Espinosa‐Fernandez (Author), Francisco J. Estrada‐Mena (Author), Ana Sofía Armenta‐Quiroga (Author), Maria Fernanda Ortega‐Treviño (Author), Rodrigo Catalán (Author), Bani Antonio‐Aguirre (Author), Cynthia Villarreal‐Garza (Author), Andric C. Perez‐Ortiz (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Taxane‐based chemotherapy regimens are used as first‐line treatment for breast cancer. Neurotoxicity, mainly taxane‐induced peripheral neuropathy (TIPN), remains the most important dose‐limiting adverse event. Multiple genes may be associated with TIPN; however, the strength and direction o...