Pharmacogenetics of taxane‐induced neurotoxicity in breast cancer: Systematic review and meta‐analysis

• मुख्य लेखकों: Alberto Guijosa (लेखक), Ana Freyria (लेखक), Jose Rodrigo Espinosa‐Fernandez (लेखक), Francisco J. Estrada‐Mena (लेखक), Ana Sofía Armenta‐Quiroga (लेखक), Maria Fernanda Ortega‐Treviño (लेखक), Rodrigo Catalán (लेखक), Bani Antonio‐Aguirre (लेखक), Cynthia Villarreal‐Garza (लेखक), Andric C. Perez‐Ortiz (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Taxane‐based chemotherapy regimens are used as first‐line treatment for breast cancer. Neurotoxicity, mainly taxane‐induced peripheral neuropathy (TIPN), remains the most important dose‐limiting adverse event. Multiple genes may be associated with TIPN; however, the strength and direction o...