Pharmacokinetic evaluation of radiolabeled intraocular anti‐CLEC14a antibody in preclinical animal species and application in humans

• मुख्य लेखकों: Sohyun Park (लेखक), Youn Woo Lee (लेखक), Jaeseong Oh (लेखक), Su Jin Kim (लेखक), Sukmook Lee (लेखक), Ho‐Young Lee (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Anti‐angiogenic antibodies are widely used in the treatment of neovascular macular degeneration. Human antibody targeting C‐type lectin domain family 14 member A (CLEC14a) is potential therapeutic agents owing to its antiangiogenic activity. In the present study, we aimed to predict the hum...