The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis.

• Main Authors: Alba Cortés (Author), John Martin (Author), Bruce A Rosa (Author), Klara A Stark (Author), Simon Clare (Author), Catherine McCarthy (Author), Katherine Harcourt (Author), Cordelia Brandt (Author), Charlotte Tolley (Author), Trevor D Lawley (Author), Makedonka Mitreva (Author), Matthew Berriman (Author), Gabriel Rinaldi (Author), Cinzia Cantacessi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing evidence shows that the host gut microbiota might be involved in the immunological cascade that culminates with the formation of tissue granulomas underlying the pathophysiology of hepato-intestinal schistosomiasis. In this study, we investigated the impact of Schistosoma mansoni infectio...