Stability and Antibiotic Potency Improvement of Levofloxacin by Producing New Salts with 2,6- and 3,5-Dihydroxybenzoic Acid and Their Comprehensive Structural Study

• Main Authors: Ilma Nugrahani (Author), Muhammad Ramadhan Sulaiman (Author), Chiaki Eda (Author), Hidehiro Uekusa (Author), Slamet Ibrahim (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Recently, solid-state engineering has become a promising approach to improving the stability and potency of antibiotics. Levofloxacin (LF) is a broad-spectrum fluoroquinolone antibiotic marketed in solid and solution dosage forms. However, this substance forms solid hydrates under ambient conditions...