Antifungal Thiazolidines: Synthesis and Biological Evaluation of Mycosidine Congeners

• Main Authors: Igor B. Levshin (Author), Alexander Y. Simonov (Author), Sergey N. Lavrenov (Author), Alexey A. Panov (Author), Natalia E. Grammatikova (Author), Alexander A. Alexandrov (Author), Eslam S. M. O. Ghazy (Author), Nikita A. Savin (Author), Peter V. Gorelkin (Author), Alexander S. Erofeev (Author), Vladimir I. Polshakov (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Novel derivatives of Mycosidine (3,5-substituted thiazolidine-2,4-diones) are synthesized by Knoevenagel condensation and reactions of thiazolidines with chloroformates or halo-acetic acid esters. Furthermore, 5-Arylidene-2,4-thiazolidinediones and their 2-thioxo analogs containing halogen and hydro...