Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis

• Main Authors: Ruizhi Wang (Author), Yongchun Wang (Author), He Liu (Author), Jinxiang Zhu (Author), Caishan Fang (Author), Weizhen Xu (Author), Zesheng Lu (Author), Yajie Yan (Author), Weiping He (Author), Yan Ruan (Author), Min Zhou (Author)
• Formato: Livro
• Publicado em: BMC, 2024-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Pyroptosis has been demonstrated being closely associated with the inflammatory progression in chronic rhinosinusitis (CRS). However, platycodon D (PLD) has emerged as a key anti-inflammatory mediator in the inflammatory progression of various respiratory diseases. This study aim...