Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet

• Päätekijät: Garima Singhal (Tekijä), Gaurav Kumar (Tekijä), Suzanne Chan (Tekijä), ffolliott M. Fisher (Tekijä), Yong Ma (Tekijä), Hilde G. Vardeh (Tekijä), Imad A. Nasser (Tekijä), Jeffrey S. Flier (Tekijä), Eleftheria Maratos-Flier (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2018-07-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Objective: Non-alcoholic fatty liver (NAFL) associated with obesity is a major cause of liver diseases which can progress to non-alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Fibroblast growth factor 21 (FGF21) plays an important role in liver metabolism and is also a pot...