Assessment of analytical techniques for characterization of crystalline clopidogrel forms in patent applications

• Main Authors: Luiz Marcelo Lira (Author), Alexandre Lopes Lourenço (Author), Guilherme Ferreira Neves (Author), Valéria Pereira de Sousa (Author), Carlos Rangel Rodrigues (Author), Lúcio Mendes Cabral (Author)
• Format: Book
• Published: Universidade de São Paulo, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to evaluate two important aspects of patent applications of crystalline forms of drugs: (i) the physicochemical characterization of the crystalline forms; and (ii) the procedure for preparing crystals of the blockbuster drug clopidogrel. To this end, searches were conducted...