TRPM7 Induces Tumorigenesis and Stemness Through Notch Activation in Glioma

• প্রধান লেখক: Jingwei Wan (লেখক), Alyssa Aihui Guo (লেখক), Pendelton King (লেখক), Shanchun Guo (লেখক), Talib Saafir (লেখক), Yugang Jiang (লেখক), Mingli Liu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

We have reported that transient receptor potential melastatin-related 7 (TRPM7) regulates glioma stem cells (GSC) growth and proliferation through Notch, STAT3-ALDH1, and CD133 signaling pathways. In this study, we determined the major contributor(s) to TRPM7 mediated glioma stemness by further deci...