Rhein Derivative 4F Inhibits the Malignant Phenotype of Breast Cancer by Downregulating Rac1 Protein

• Glavni autori: Xinxiao Li (Autor), Yunfeng Liu (Autor), Yuhua Zhao (Autor), Wei Tian (Autor), Lina Zhai (Autor), Huifeng Pang (Autor), Jiankang Kang (Autor), Huaxin Hou (Autor), Yanhua Chen (Autor), Danrong Li (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

BackgroundTriple-negative breast cancer is a common malignant tumor with unfavorable prognosis affecting women worldwide; thus, there is an urgent need for novel therapeutic drugs with improved anti-tumor activity. Rac family small GTPase 1 (Rac1) plays an important role in malignant behavior and is...