β1 integrins as therapeutic targets to disrupt hallmarks of cancer

• मुख्य लेखकों: Anne-Florence eBlandin (लेखक), Guillaume eRenner (लेखक), Isabelle eLelong-Rebel (लेखक), Sophie eMartin (लेखक), Maxime eLehmann (लेखक), Monique eDontenwill (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Integrins belong to a large family of αβ heterodimeric transmembrane proteins first recognized as adhesion molecules that bind to dedicated elements of the extracellular matrix and also to other surrounding cells. As important sensors of the cell microenvironment, they regulate numerous signaling pa...