Anticancer Activity of 4-Aryl-1,4-Dihydropyridines

• Main Authors: Thaís A. S. Oliveira (Author), Jackson B. A. Silva (Author), Tábata R. Esperandim (Author), Nathália O. Acésio (Author), Denise C. Tavares (Author), Antônio E. M. Crotti (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a "green" microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human glioblastoma), HeLa 229 (human cervical...