A Cre-driver rat model for anatomical and functional analysis of glucagon (Gcg)-expressing cells in the brain and periphery

• Үндсэн зохиолчид: Huiyuan Zheng (Зохиогч), Lorena López-Ferreras (Зохиогч), Jean-Phillipe Krieger (Зохиогч), Stephen Fasul (Зохиогч), Valentina Cea Salazar (Зохиогч), Natalia Valderrama Pena (Зохиогч), Karolina P. Skibicka (Зохиогч), Linda Rinaman (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2022-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Objective: The glucagon gene (Gcg) encodes preproglucagon, which is cleaved to form glucagon-like peptide 1 (GLP1) and other mature signaling molecules implicated in metabolic functions. To date there are no transgenic rat models available for precise manipulation of GLP1-expressing cells in the bra...