An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

• Main Authors: Callie E. Bounds (Author), Frances E. Terry (Author), Leonard Moise (Author), Drew Hannaman (Author), William D. Martin (Author), Anne S. De Groot (Author), John J. Suschak (Author), Lesley C. Dupuy (Author), Connie S. Schmaljohn (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunoinformatics tools were used to predict human leukocyte antigen (HLA) class II-restricted T cell epitopes within the envelope glycoproteins and nucleocapsid proteins of Ebola virus (EBOV) and Sudan virus (SUDV) and the structural proteins of Venezuelan equine encephalitis virus (VEEV). Selected...