Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation

• Main Authors: Núria DeGregorio-Rocasolano (Author), Verónica Guirao (Author), Jovita Ponce (Author), Marc Melià-Sorolla (Author), Alicia Aliena-Valero (Author), Alexia García-Serran (Author), Juan B. Salom (Author), Antoni Dávalos (Author), Octavi Martí-Sistac (Author), Teresa Gasull (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Death-associated protein kinase 1 (DAPK1) is a pleiotropic hub of a number of networked distributed intracellular processes. Among them, DAPK1 is known to interact with the excitotoxicity driver NMDA receptor (NMDAR), and in sudden pathophysiological conditions of the brain, e.g., stroke, several li...