Targeted Drug Delivery to the Central Nervous System Using Extracellular Vesicles

• Main Authors: Lina Zhou (Author), Sunitha Kodidela (Author), Sandip Godse (Author), Stacey Thomas-Gooch (Author), Asit Kumar (Author), Babatunde Raji (Author), Kaining Zhi (Author), Harry Kochat (Author), Santosh Kumar (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The blood brain barrier (BBB) maintains the homeostasis of the central nervous system (CNS) and protects the brain from toxic substances present in the circulating blood. However, the impermeability of the BBB to drugs is a hurdle for CNS drug development, which hinders the distribution of the most...