Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration

• Main Authors: Jouda Gamara (Author), Lynn Davis (Author), Emmanuelle Rollet-Labelle (Author), Tsunaki Hongu (Author), Yuji Funakoshi (Author), Yasunori Kanaho (Author), Fawzi Aoudjit (Author), Sylvain G. Bourgoin (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemoattractant sensing, adhesiveness, and migration are critical events underlying the recruitment of neutrophils (PMNs) to sites of inflammation or infection. Defects in leukocyte adhesion or migration result in immunodeficiency disorders characterized by recurrent infections. In this study, we ev...