Clinical Feature, Treatment, and KCNH5 Mutations in Epilepsy

• Main Authors: Xiufu Hu (Author), Junli Yang (Author), Man Zhang (Author), Tie Fang (Author), Qin Gao (Author), Xinjie Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The voltage-gated Kv10.2 potassium channel, encoded by KCNH5, is broadly expressed in mammalian tissues, including the brain. Its potential mechanism remains unclear. According to previous studies, dysfunction of Kv10.2 may be associated with epileptic encephalopathies and autism spectrum disorder (...