A novel nitidine chloride nanoparticle overcomes the stemness of CD133+EPCAM+ Huh7 hepatocellular carcinoma cells for liver cancer therapy

Abstract Background Stemness of CD133+EPCAM+ hepatocellular carcinoma cells ensures cancer resistance to apoptosis,which is a challenge to current liver cancer treatments. In this study, we evaluated the tumorcidal activity of a novel nanoparticle of nitidine chloride (TPGS-FA/NC, TPGS-FA: folic aci...

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Main Authors: Danni Li (Author), Qiying Zhang (Author), Yuzhu Zhou (Author), Hua Zhu (Author), Tong Li (Author), Fangkai Du (Author)
Format: Book
Published: BMC, 2022-07-01T00:00:00Z.
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