Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury

• Asıl Yazarlar: Melissa Jones (Yazar), Jie Wen (Yazar), Prabhuanand Selvaraj (Yazar), Mikiei Tanaka (Yazar), Sean Moran (Yazar), Yumin Zhang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Enhancement of endocannabinoid signaling has emerged as an attractive strategy for the treatment of pain. In addition to the well-characterized hydrolytic pathways, cyclooxygenase-2 (COX-2) mediated oxygenation is thought to be an alternative route for endocannabinoid metabolism and therefore provid...