Inhibition of Ocular Aldose Reductase by a New Benzofuroxane Derivative Ameliorates Rat Endotoxic Uveitis

• Main Authors: C. Di Filippo (Author), M. V. Zippo (Author), R. Maisto (Author), M. C. Trotta (Author), D. Siniscalco (Author), B. Ferraro (Author), F. Ferraraccio (Author), C. La Motta (Author), S. Sartini (Author), S. Cosconati (Author), E. Novellino (Author), C. Gesualdo (Author), F. Simonelli (Author), S. Rossi (Author), M. D'Amico (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study investigated the effects of the aldose reductase (AR) inhibitor benzofuroxane derivative 5(6)-(benzo[d]thiazol-2-ylmethoxy) benzofuroxane (herein referred to as BF-5m) on the biochemical and tissue alterations induced by endotoxic uveitis in rats. BF-5m has been administered directly into...