High Serum Levels of Toxin A Correlate with Disease Severity in Patients with <i>Clostridioides difficile</i> Infection

• Main Authors: Guido Granata (Author), Davide Mariotti (Author), Paolo Ascenzi (Author), Nicola Petrosillo (Author), Alessandra di Masi (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Cloistridioides difficile</i> (CD) represents a major public healthcare-associated infection causing significant morbidity and mortality. The pathogenic effects of CD are mainly caused by the release of two exotoxins into the intestine: toxin A (TcdA) and toxin B (TcdB). CD infection...