Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination

• Main Authors: Xibao Zhao (Author), Debing Pu (Author), Zizhao Zhao (Author), Huihui Zhu (Author), Hongrui Li (Author), Yaping Shen (Author), Xingjie Zhang (Author), Ruihan Zhang (Author), Jianzhong Shen (Author), Weilie Xiao (Author), Weilin Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammation causes many diseases that are serious threats to human health. However, the molecular mechanisms underlying regulation of inflammation and inflammasome activation are not fully understood which has delayed the discovery of new anti-inflammatory drugs of urgent clinic need. Here, we foun...