Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy

Kappa opioid receptors have exceptional potential as an analgesic target, seemingly devoid of many problematic Mu receptor side-effects. Kappa-selective, small molecule pharmaceutical agents have been developed, but centrally mediated side-effects limit clinical translation. We modify endogenous dyn...

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Main Authors: Rink-Jan Lohman (Author), Karnaker Reddy Tupally (Author), Ajit Kandale (Author), Peter J. Cabot (Author), Harendra S. Parekh (Author)
Format: Book
Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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