Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy
Kappa opioid receptors have exceptional potential as an analgesic target, seemingly devoid of many problematic Mu receptor side-effects. Kappa-selective, small molecule pharmaceutical agents have been developed, but centrally mediated side-effects limit clinical translation. We modify endogenous dyn...
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Main Authors: | Rink-Jan Lohman (Author), Karnaker Reddy Tupally (Author), Ajit Kandale (Author), Peter J. Cabot (Author), Harendra S. Parekh (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2023-03-01T00:00:00Z.
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