Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

Protein kinase CK2, initially designated as casein kinase 2, is an ubiquitously expressed serine/threonine kinase. This enzyme, implicated in many cellular processes, is highly expressed and active in many tumor cells. A large number of compounds has been developed as inhibitors comprising different...

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Main Authors: Samer Haidar (Author), Zouhair Bouaziz (Author), Christelle Marminon (Author), Tuomo Laitinen (Author), Antti Poso (Author), Marc Le Borgne (Author), Joachim Jose (Author)
Format: Book
Published: MDPI AG, 2017-01-01T00:00:00Z.
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