Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells

• Váldodahkkit: Guanglong Zhang (Dahkki), Zhenhua Tang (Dahkki), Sili Fan (Dahkki), Chengpeng Li (Dahkki), Yan Li (Dahkki), Weiqin Liu (Dahkki), Xuesha Long (Dahkki), Wenjing Zhang (Dahkki), Yi Zhang (Dahkki), Zhurui Li (Dahkki), Zhenchao Wang (Dahkki), Danping Chen (Dahkki), Guiping Ouyang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Herein, a new series of 2-chloro-N-(5-(2-oxoindolin-3-yl)-4H-pyrazol-3-yl) acetamide derivatives containing 1,3,4-thiadiazole (10a-i) and 4H-1,2,4-triazol-4-amine (11a-r) moiety was designed, synthesised as novel anticancer agents. The antiproliferative activity values indicated that compound 10 b s...