Quality by Design Approach for the Development of Liposome Carrying Ghrelin for Intranasal Administration

• Main Authors: Cecília de Barros (Author), Norberto Aranha (Author), Patrícia Severino (Author), Eliana B. Souto (Author), Aleksandra Zielińska (Author), André Lopes (Author), Alessandra Rios (Author), Fernando Batain (Author), Kessi Crescencio (Author), Marco Chaud (Author), Thais Alves (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The therapeutic use of peptides has increasingly recognized in the development of new therapies. However, the susceptible enzymatic cleavage is a barrier that needs to overcome. Nose-to-brain delivery associated with liposomes can protect peptides against biodegradation and improve the accessibility...