miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling

• Main Authors: Lihui Zhang (Author), Liwen Yao (Author), Wei Zhou (Author), Jinping Tian (Author), Banlai Ruan (Author), Zihua Lu (Author), Yunchao Deng (Author), Qing Li (Author), Zhi Zeng (Author), Dongmei Yang (Author), Renduo Shang (Author), Ming Xu (Author), Mengjiao Zhang (Author), Du Cheng (Author), Yanning Yang (Author), Qianshan Ding (Author), Honggang Yu (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric cancer (GC) is one of the leading causes of cancer-related death worldwide. MicroRNAs (miRNAs) are known to be important regulators of GC. This study aims to investigate the role of miRNA (miR)-497 in GC. We demonstrated that the expression of miR-497 was downregulated in human GC tissues. A...