Rare case of chemotherapy-refractory metastatic vaginal squamous cell carcinoma with complete response to concurrent pembrolizumab and radiotherapy- case report and literature review

• Main Authors: Jawaher Ansari (Author), Yussra Eltigani Mohmmed (Author), Saad Ghazal-Aswad (Author), Hidayath Ansari (Author), Syed M.J. Akhter (Author), Omar Hassoun Hadid (Author), Syed Rizwan (Author), Raya Almazrouei (Author), Emad Dawoud (Author), Fathi Azribi (Author), Heba Elhasin (Author), Pawan Kumar (Author), Abdul Rahman Al Sumaida (Author), Khaled Al-Qawasmeh (Author), John Glaholm (Author), M.J. Hochmair (Author), Syed Hussain (Author), Khalid Balaraj (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Primary vaginal cancer is a rare malignancy with a lack of international guidelines and supporting clinical trial evidence to guide decision making. Historical results have shown poor outcomes with chemotherapy for stage IVB vaginal squamous cell carcinoma (SCC). The evolving role of checkpoint inhi...