Nitroxide-HMP-Protects Human Trophoblast HTR-8/SVneo Cells from H₂O₂-Induced Oxidative Stress by Reducing the HIF1A Signaling Pathway

• Auteurs principaux: Diana Pintye (Auteur), Réka Eszter Sziva (Auteur), Maxim Mastyugin (Auteur), Marianna Török (Auteur), Sonako Jacas (Auteur), Agnes Lo (Auteur), Saira Salahuddin (Auteur), Zsuzsanna K. Zsengellér (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Preeclampsia (PE) is a pregnancy-specific syndrome affecting 5-7% of patients. There is no effective treatment available. Early abnormal placental development is associated with oxidative stress (OS) and a release of reactive oxygen species (ROS) in the placenta. This phenomenon leads to downstream...