Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway

• Main Authors: Qianqian Zhang (Author), Min Yao (Author), Jiajia Qi (Author), Rui Song (Author), Lei Wang (Author), Jiacheng Li (Author), Xian Zhou (Author), Dennis Chang (Author), Qi Huang (Author), Lili Li (Author), Ning Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Puerarin (PUE) is a natural compound isolated from Puerariae Lobatae Radix, which has a neuroprotective effect on IS. We explored the therapeutic effect and underlying mechanism of PUE on cerebral I/R injury by inhibiting oxidative stress related to the PI3K/Akt/Nrf2 pathway in vitro a...