Antimicrobial De-Escalation in Critically Ill Patients

• Main Authors: Eloisa Sofia Tanzarella (Author), Salvatore Lucio Cutuli (Author), Gianmarco Lombardi (Author), Fabiola Cammarota (Author), Alessandro Caroli (Author), Emanuele Franchini (Author), Elena Sancho Ferrando (Author), Domenico Luca Grieco (Author), Massimo Antonelli (Author), Gennaro De Pascale (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antimicrobial de-escalation (ADE) is defined as the discontinuation of one or more antimicrobials in empirical therapy, or the replacement of a broad-spectrum antimicrobial with a narrower-spectrum antimicrobial. The aim of this review is to provide an overview of the available literature on the eff...