Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations

<p>Abstract</p> <p>Background</p> <p>Genome-wide association studies give insight into the genetic basis of common diseases. An open question is whether the allele frequency distributions and ancestral vs. derived states of disease-associated alleles differ from the res...

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Main Author: Lachance Joseph (Author)
Format: Book
Published: BMC, 2010-12-01T00:00:00Z.
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3rd Floor Main Library

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