Formulation of a modified release metformin. HCl matrix tablet: influence of some hydrophilic polymers on release rate and in-vitro evaluation

Metformin hydrochloride is an antidiabetic agent which improves glucose tolerance in patients with type 2 diabetes and reduces basal plasma levels of glucose. In this study, a simplex centroid experimental design with 69 runs was used to select the best combination of some hydrophilic polymers that...

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Main Authors: John Rojas (Author), Cesar González (Author), Carolina Rico (Author), Oswaldo Saez (Author)
Format: Book
Published: Universidade de São Paulo, 2011-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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