Formulation of a modified release metformin. HCl matrix tablet: influence of some hydrophilic polymers on release rate and in-vitro evaluation
Metformin hydrochloride is an antidiabetic agent which improves glucose tolerance in patients with type 2 diabetes and reduces basal plasma levels of glucose. In this study, a simplex centroid experimental design with 69 runs was used to select the best combination of some hydrophilic polymers that...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Universidade de São Paulo,
2011-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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