Characterization of the absorption, metabolism, excretion, and mass balance of gefapixant in humans
Abstract Gefapixant (MK‐7264) is a first‐in‐class, selective antagonist of the P2X3 purinergic receptor currently being investigated as a therapeutic agent for the treatment of refractory or unexplained chronic cough. In non‐clinical studies, gefapixant was eliminated primarily by renal excretion of...
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Main Authors: | Jesse C. Nussbaum (Author), Azher Hussain (Author), Bennett Ma (Author), K. Chris Min (Author), Qing Chen (Author), Charles Tomek (Author), Marian Iwamoto (Author), S. Aubrey Stoch (Author) |
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Format: | Book |
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Wiley,
2022-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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