Molecular mechanisms involved in the IL-6-mediated upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression in the chorionic villi and decidua of women in early pregnancy

• Main Authors: Rui Wang (Author), Shuyun Zhao (Author), Xiaojuan Chen (Author), Ziwen Xiao (Author), Xinghui Wen (Author), Xingming Zhong (Author), Shixiang Li (Author), Hui Cheng (Author), Guanyou Huang (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background IL-6 induces the upregulation of indoleamine 2,3-dioxygenase (IDO1) at the maternal-foetal interface, but the regulation mechanisms of IDO1 by IL-6 at this interface have not been fully understood. Methods Western blotting, qRT-PCR and/or immunohistochemistry were employed to mea...