Missed Cystic Fibrosis Newborn Screening Cases due to Immunoreactive Trypsinogen Levels below Program Cutoffs: A National Survey of Risk Factors

• Main Authors: Martin Kharrazi (Author), Charlene Sacramento (Author), Anne Marie Comeau (Author), Jaime E. Hale (Author), Michele Caggana (Author), Denise M. Kay (Author), Rachel Lee (Author), Brendan Reilly (Author), John D. Thompson (Author), Samya Z. Nasr (Author), Mary Kleyn (Author), Gary Hoffman (Author), Mei W. Baker (Author), Colleen Clarke (Author), Cheryl L. Harris (Author), M. Christine Dorley (Author), Hilary Fryman (Author), Ankit Sutaria (Author), Amy Hietala (Author), Holly Winslow (Author), Holly Richards (Author), Bradford L. Therrell (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Testing immunoreactive trypsinogen (IRT) is the first step in cystic fibrosis (CF) newborn screening. While high IRT is associated with CF, some cases are missed. This survey aimed to find factors associated with missed CF cases due to IRT levels below program cutoffs. Twenty-nine states responded t...