Epithelioid granulomatous lesions express abundant programmed death ligand-1 (PD-L1): a discussion of adverse events in anti-PD-1 antibody-based cancer immunotherapy

• Main Authors: Terufumi Kubo (Author), Yoshihiko Hirohashi (Author), Tomohide Tsukahara (Author), Takayuki Kanaseki (Author), Kenji Murata (Author), Tadashi Hasegawa (Author), Toshihiko Torigoe (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The immune system is often called a double-edged sword, due to the inextricable link between cancer immunity and allergy/autoimmunity. Intriguingly, a growing number of cases have been reported in which PD-1 blockade triggers the exacerbation of tuberculosis (TB), an organ-invasive granulomatous dis...