Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells
Glioblastoma stem cells (GSCs) are invasive, treatment-resistant brain cancer cells that express downregulated in renal cell carcinoma (DRR), also called FAM107A, a genetic driver of GSC invasion. We developed antibody-antisense oligonucleotide (AON) conjugates to target and reduce DRR/FAM107A expre...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Elsevier,
2018-06-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |