How does the NPM1 mutant induce leukemia?

NPM1 is the most frequently mutated gene in AML and the role of the NPM1 mutant in acute myeloid leukemia along with its leukemogenic potential are still under investigation. NPM1 genetic alterations can contribute to leukemogenesis through the direct oncogenic effect of the mutant protein and the c...

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Bibliographic Details
Main Author: Paolo Sportoletti (Author)
Format: Book
Published: MDPI AG, 2011-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available