Evaluation of Pharmacokinetics and Pharmacodynamics of Deferasirox in Pediatric Patients

Evaluation of Pharmacokinetics and Pharmacodynamics of Deferasirox in Pediatric Patients

Background: Deferasirox (DFX) is commonly used to reduce the chronic iron overload (IO) in pediatric patients. However, the drug is characterized by a large pharmacokinetic variability and approximately 10% of patients may discontinue the treatment due to toxicities. Therefore, the present retrospec...

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Main Authors: Laura Galeotti (Author), Francesco Ceccherini (Author), Carmen Fucile (Author), Valeria Marini (Author), Antonello Di Paolo (Author), Natalia Maximova (Author), Francesca Mattioli (Author)
Format: Book
Published: MDPI AG, 2021-08-01T00:00:00Z.
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