Evaluation of Pharmacokinetics and Pharmacodynamics of Deferasirox in Pediatric Patients

• Asıl Yazarlar: Laura Galeotti (Yazar), Francesco Ceccherini (Yazar), Carmen Fucile (Yazar), Valeria Marini (Yazar), Antonello Di Paolo (Yazar), Natalia Maximova (Yazar), Francesca Mattioli (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Deferasirox (DFX) is commonly used to reduce the chronic iron overload (IO) in pediatric patients. However, the drug is characterized by a large pharmacokinetic variability and approximately 10% of patients may discontinue the treatment due to toxicities. Therefore, the present retrospec...