DDIT: An Online Predictor for Multiple Clinical Phenotypic Drug-Disease Associations

• Main Authors: Lu Lu (Author), Jiale Qin (Author), Jiandong Chen (Author), Hao Wu (Author), Qiang Zhao (Author), Satoru Miyano (Author), Yaozhong Zhang (Author), Hua Yu (Author), Chen Li (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Drug repurposing provides an effective method for high-speed, low-risk drug development. Clinical phenotype-based screening exceeded target-based approaches in discovering first-in-class small-molecule drugs. However, most of these approaches predict only binary phenotypic associations b...