Interrogating islets in health and disease with single-cell technologies

• Principais autores: Andrea C. Carrano (Autor), Francesca Mulas (Autor), Chun Zeng (Autor), Maike Sander (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2017-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Blood glucose levels are tightly controlled by the coordinated actions of hormone-producing endocrine cells that reside in pancreatic islets. Islet cell malfunction underlies diabetes development and progression. Due to the cellular heterogeneity within islets, it has been challenging to...